Endocrine Abstracts

Von Hippel-Lindau (VHL) syndrome is a pathological condition that causes various clinical symptoms and is difficult to diagnose. The most common pathological lesions are hemangioblastomas of the central nervous system, retinal angiomas, renal clear cell carcinomas, and pheochromocytomas. Here we reposrt a case of likely to be VHL due to his family history.Case: A 33-year-old male suffering from hypertension and a history of hemangioblastoma operated in 2...

Background: Primary Hyperparathyroidism (PHPT) is a common endocrine disorder that is characterized by hypercalcaemia and elevated or inappropriately normal serum levels of parathyroid hormone. Most often, the presentation of PHPT is asymptomatic. PHPT can manifest with osteoporosis and hypercalciuria as well as with vertebral fractures and nephrolithiasis, both of which can be asymptomatic. Our aim in this study; to determine the frequency of kidney stones in patients operate...

Background: Micro vascular complications are the major outcome of Type 2 Diabetes Mellitus progression, which reduces the quality of life and increases diabetic morbidity & mortality. As the incidence of type 2 diabetes is growing day by day; our search for its aetiology and pathogenesis is also ever growing to predict its risk factors and early screening for better care and prevention of its complications. Many studies have tried to link susceptibility of type 2 diabetes ...

Aim: Although thyroid nodules located in isthmus were less frequent, papillary thyroid cancer in this location was reported to be more aggressive in some studies. Our aim was to evaluate hormonal, ultrasonographic, and cytopathologic features of nodules located in isthmus (isthmic nodules).Material and methods: Data of patients who underwent thyroidectomy between 2006–2014 were reviewed retrospectively. Hormonal, ultrasonographic, and cytopathologic...

Aim: It has been reported that thyrotrophin receptor antibody (TRAb) is associated with frequency and aggressiveness of thyroid cancer in patients with Graves disease (GD). However, there is not any data regarding the effects of TRAb on cytology and histopathology results of patients with nodular GD. Thus, the aim of the present study is to evaluate the effects of TRAb on cytology and histopathology results in patients with nodular or multinodular thyroid disease on the basis ...

Aim: In this study we aimed to evaluate the oxidative stress via evaluating changes in dynamic thiol-disulphide status in euthyroid patients with Hashimoto’s thyroiditis (HT).Methods: Fifty euthyroid patients with HT and 50 healthy individuals were enrolled in this study. Thyroid function tests (free triiodothyronine (fT3), free thyroxine (fT4), thyrotropin (TSH)), acute phase reactants (C-reactive protein (CRP), high sensitive CRP (hs-CRP)) and thi...

Aim: Atypia/follicular lesion of undetermined significance(AUS/FLUS) is a category of thyroid cytology with features that are neither definitely benign or malignant. We aimed to determine whether specific cytologic or architectural features are associated with malignancy in AUS/FLUS category of Bethesda system according to subgroups.Methods: The specimens of patients who underwent surgery with preoperative thyroid fine neeedle aspiration (FNA) biopsies o...

Introduction: Although malignancy rate is low in thyroid nodules with nondiagnostic (ND) cytology, it is reported as higher in persistent ND nodules. We aimed to determine the role of ultrasonography (US) features and Thyroid Imaging Reporting and Data System (TIRADS) in the prediction of malignancy in patients with persistent ND cytology.Methods: 246 patients who underwent thyroidectomy with an indication of at least two ND cytologies were included in t...

Introduction: Recently, it has been suggested that thyrotropin (TSH) concentration can be used as a marker for prediction of thyroid malignancy. However, the association between the cytology results and TSH levels is not clear. In this study, we aimed to investigate the relationship between TSH levels and Bethesda categories and determine the role of TSH levels in prediction of malignancy in patients with different Bethesda categories.Methods: The data o...

Introduction: Incidental thyroid carcinoma (ITC) in patients operated on for a benign disease is frequent. ITC characteristics in patients operated for malign disease, but not sampled by fine needle aspiration (FNA) or seen in ultrasonography, is unknown. We aimed to compare ITC with nonincidental ITC (NITC) in this study.Material and method: Retrospective analyses of 918 individual patients who were operated for benign and malign thyroid disease in our ...